This list contains all of Dr. Bhakdi’s papers which are found on PubMed, as of January 2023.

  1. Leitzke, S. et al. (2022) Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function. Membranes (Basel) 12 (PubMed: 35207044)
  2. Reiss, K. et al. (2022) Scramblases as Regulators of Proteolytic ADAM Function. Membranes (Basel) 12 (PubMed: 35207106)
  3. Seidel, J. et al. (2021) Role of ADAM10 and ADAM17 in Regulating CD137 Function. Int J Mol Sci 22 (PubMed: 33800462)
  4. Bleibaum, F. et al. (2019) ADAM10 sheddase activation is controlled by cell membrane asymmetry. J Mol Cell Biol 11:979-993 (PubMed: 30753537)
  5. Veit, M. et al. (2019) Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice. Life Sci Alliance 2 (PubMed: 31455669)
  6. Veit, M. et al. (2018) Anoctamin-6 regulates ADAM sheddase function. Biochim Biophys Acta Mol Cell Res 1865:1598-1610 (PubMed: 30327201)
  7. Reiss, K. and Bhakdi, S. (2017) The plasma membrane: Penultimate regulator of ADAM sheddase function. Biochim Biophys Acta Mol Cell Res 1864:2082-2087 (PubMed: 28624437)
  8. Sommer, A. et al. (2017) Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding. Oncotarget 8:72584-72596 (PubMed: 29069811)
  9. Sommer, A. et al. (2016) Phosphatidylserine exposure is required for ADAM17 sheddase function. Nat Commun 7:11523 (PubMed: 27161080)
  10. Sommer, A. et al. (2016) How membrane asymmetry regulates ADAM17 sheddase function. Cell Cycle 15:2995-2996 (PubMed: 27463373)
  11. Dasari, P. et al. (2014) Malarial anemia: digestive vacuole of Plasmodium falciparum mediates complement deposition on bystander cells to provoke hemophagocytosis. Med Microbiol Immunol 203:383-93 (PubMed: 24985035)
  12. Torzewski, M. and Bhakdi, S. (2013) Complement and atherosclerosis-united to the point of no return?. Clin Biochem 46:20-5 (PubMed: 23010447)
  13. Bal, G. et al. (2013) Proteomic profiling of secreted proteins for the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells. Cell Transplant 22:1185-99 (PubMed: 23031318)
  14. Dasari, P. et al. (2012) Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation. Blood 119:4301-10 (PubMed: 22403252)
  15. Bhakdi, S. et al. (2012) Use of quantitative microbiological analyses to trace origin of contamination of parenteral nutrition solutions. Med Microbiol Immunol 201:231-7 (PubMed: 22484833)
  16. Sommer, A. et al. (2012) Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation. J Biol Chem 287:23678-89 (PubMed: 22613720)
  17. Dasari, P. and Bhakdi, S. (2012) Pathogenesis of malaria revisited. Med Microbiol Immunol 201:599-604 (PubMed: 22955244)
  18. Reiss, K. and Bhakdi, S. (2012) Pore-forming bacterial toxins and antimicrobial peptides as modulators of ADAM function. Med Microbiol Immunol 201:419-26 (PubMed: 22972233)
  19. Bhakdi, S. (2012) Mechanisms of invasion and persistence of infectious agents. Med Microbiol Immunol 201:407 (PubMed: 23001362)
  20. Reiss, K. et al. (2011) Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity. J Biol Chem 286:26931-42 (PubMed: 21642425)
  21. Dasari, P. et al. (2011) Digestive vacuoles of Plasmodium falciparum are selectively phagocytosed by and impair killing function of polymorphonuclear leukocytes. Blood 118:4946-56 (PubMed: 21911835)
  22. Metz, M. et al. (2009) Mast cells determine the magnitude of bacterial toxin-induced skin inflammation. Exp Dermatol 18:160-6 (PubMed: 18643847)
  23. Reifenberg, K. et al. (2009) Endotoxin accelerates atherosclerosis independent of complement activation. Thromb Res 123:653-8 (PubMed: 18692867)
  24. Husmann, M. et al. (2009) Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis. FEBS Lett 583:337-44 (PubMed: 19101547)
  25. Torzewski, M. et al. (2009) Investigation of Sudan IV staining areas in aortas of infants and children: possible prelesional stages of atherogenesis. Atherosclerosis 206:159-67 (PubMed: 19268943)
  26. Löhner, S. et al. (2009) Pore formation by Vibrio cholerae cytolysin follows the same archetypical mode as beta-barrel toxins from gram-positive organisms. FASEB J 23:2521-8 (PubMed: 19276173)
  27. Lux, C.A. et al. (2009) Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein. Atherosclerosis 207:116-22 (PubMed: 19423111)
  28. Kloft, N. et al. (2009) Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium. Biochem Biophys Res Commun 385:503-6 (PubMed: 19497299)
  29. Bhakdi, S. et al. (2009) Possible hidden hazards of mass vaccination against new influenza A/H1N1: have the cardiovascular risks been adequately weighed?. Med Microbiol Immunol 198:205-9 (PubMed: 19851782)
  30. Koike, T. et al. (2009) Human C-reactive protein does not promote atherosclerosis in transgenic rabbits. Circulation 120:2088-94 (PubMed: 19901190)
  31. Valeva, A. et al. (2008) Pro-inflammatory feedback activation cycle evoked by attack of Vibrio cholerae cytolysin on human neutrophil granulocytes. Med Microbiol Immunol 197:285-93 (PubMed: 17882454)
  32. Torzewski, M. et al. (2008) No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice. Thromb Haemost 99:196-201 (PubMed: 18217154)
  33. Schwarz, M. et al. (2008) Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity. Thromb Haemost 100:110-8 (PubMed: 18612545)
  34. Valeva, A. et al. (2008) Putative identification of an amphipathic alpha-helical sequence in hemolysin of Escherichia coli (HlyA) involved in transmembrane pore formation. Biol Chem 389:1201-7 (PubMed: 18713007)
  35. Fenske, D. et al. (2008) Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells. Thromb Haemost 100:1146-54 (PubMed: 19132242)
  36. Grüner, B.M. et al. (2007) Characterization of a catalase-negative methicillin-resistant Staphylococcus aureus strain. J Clin Microbiol 45:2684-5 (PubMed: 17581939)
  37. Avirutnan, P. et al. (2006) Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J Infect Dis 193:1078-88 (PubMed: 16544248)
  38. Koschinski, A. et al. (2006) Why Escherichia coli alpha-hemolysin induces calcium oscillations in mammalian cells–the pore is on its own. FASEB J 20:973-5 (PubMed: 16597673)
  39. Husmann, M. et al. (2006) Differential role of p38 mitogen activated protein kinase for cellular recovery from attack by pore-forming S. aureus alpha-toxin or streptolysin O. Biochem Biophys Res Commun 344:1128-34 (PubMed: 16643845)
  40. Petry, F. et al. (2006) Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid. J Clin Microbiol 44:1903-4 (PubMed: 16672436)
  41. Valeva, A. et al. (2006) Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore. J Biol Chem 281:26014-21 (PubMed: 16829693)
  42. Haugwitz, U. et al. (2006) Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferation. Cell Microbiol 8:1591-600 (PubMed: 16984414)
  43. Bhakdi, S. (2006) [Immunopathogenesis of atherosclerosis: the Mainz hypothesis]. Med Monatsschr Pharm 29:356-9 (PubMed: 17058894)
  44. Dersch, K. et al. (2005) Fatty acids liberated from low-density lipoprotein trigger endothelial apoptosis via mitogen-activated protein kinases. Cell Death Differ 12:1107-14 (PubMed: 15846374)
  45. Reifenberg, K. et al. (2005) Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?. Arterioscler Thromb Vasc Biol 25:1641-6 (PubMed: 15920030)
  46. Valeva, A. et al. (2005) Identification of the membrane penetrating domain of Vibrio cholerae cytolysin as a beta-barrel structure. Mol Microbiol 57:124-31 (PubMed: 15948954)
  47. Valeva, A. et al. (2005) Binding of Escherichia coli hemolysin and activation of the target cells is not receptor-dependent. J Biol Chem 280:36657-63 (PubMed: 16131494)
  48. Dalla Serra, M. et al. (2005) Staphylococcus aureus bicomponent gamma-hemolysins, HlgA, HlgB, and HlgC, can form mixed pores containing all components. J Chem Inf Model 45:1539-45 (PubMed: 16309251)
  49. Bhakdi, S. et al. (2004) Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence. Circulation 109:1870-6 (PubMed: 15037531)
  50. Bhakdi, S. et al. (2004) Beyond cholesterol: the enigma of atherosclerosis revisited. Thromb Haemost 91:639-45 (PubMed: 15045123)
  51. Valeva, A. et al. (2004) A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin. J Biol Chem 279:25143-8 (PubMed: 15066987)
  52. Torzewski, M. et al. (2004) Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis. Arterioscler Thromb Vasc Biol 24:2130-6 (PubMed: 15345515)
  53. Han, S. et al. (2003) Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis. Arterioscler Thromb Vasc Biol 23:661-7 (PubMed: 12615673)
  54. Bhakdi, S. and Bohl, J. (2003) Prions, mad cow disease, and preventive measures: a critical appraisal. Med Microbiol Immunol 192:117-22 (PubMed: 12819966)
  55. Bhakdi, S. (2003) An hypothesis for the immunopathogenesis of atherosclerosis. Clin Nephrol 60 Suppl 1:S49-52 (PubMed: 12940533)
  56. Stassen, M. et al. (2003) The streptococcal exotoxin streptolysin O activates mast cells to produce tumor necrosis factor alpha by p38 mitogen-activated protein kinase- and protein kinase C-dependent pathways. Infect Immun 71:6171-7 (PubMed: 14573633)
  57. Walev, I. et al. (2002) Resealing of large transmembrane pores produced by streptolysin O in nucleated cells is accompanied by NF-kappaB activation and downstream events. FASEB J 16:237-9 (PubMed: 11744625)
  58. Bhakdi, S. (2002) [Immunopathogenesis of atherosclerosis: the Mainz hypothesis]. Dtsch Med Wochenschr 127:390-4 (PubMed: 11859449)
  59. Gerl, V.B. et al. (2002) Extensive deposits of complement C3d and C5b-9 in the choriocapillaris of eyes of patients with diabetic retinopathy. Invest Ophthalmol Vis Sci 43:1104-8 (PubMed: 11923252)
  60. Horstick, G. et al. (2002) Early albumin infusion improves global and local hemodynamics and reduces inflammatory response in hemorrhagic shock. Crit Care Med 30:851-5 (PubMed: 11940758)
  61. Harris, J.R. et al. (2002) Interaction of the Vibrio cholerae cytolysin (VCC) with cholesterol, some cholesterol esters, and cholesterol derivatives: a TEM study. J Struct Biol 139:122-35 (PubMed: 12406694)
  62. Suriyaphol, P. et al. (2002) Enzymatically modified nonoxidized low-density lipoprotein induces interleukin-8 in human endothelial cells: role of free fatty acids. Circulation 106:2581-7 (PubMed: 12427655)
  63. Baumeister, S. et al. (2001) Selective permeabilization of infected host cells with pore-forming proteins provides a novel tool to study protein synthesis and viability of the intracellular apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii. Mol Biochem Parasitol 112:133-7 (PubMed: 11166394)
  64. Schindel, C. et al. (2001) Interaction of Escherichia coli hemolysin with biological membranes. A study using cysteine scanning mutagenesis. Eur J Biochem 268:800-8 (PubMed: 11168421)
  65. Walev, I. et al. (2001) Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O. Proc Natl Acad Sci U S A 98:3185-90 (PubMed: 11248053)
  66. Dragneva, Y. et al. (2001) Subcytocidal attack by staphylococcal alpha-toxin activates NF-kappaB and induces interleukin-8 production. Infect Immun 69:2630-5 (PubMed: 11254628)
  67. Zitzer, A. et al. (2001) Coupling of cholesterol and cone-shaped lipids in bilayers augments membrane permeabilization by the cholesterol-specific toxins streptolysin O and Vibrio cholerae cytolysin. J Biol Chem 276:14628-33 (PubMed: 11279036)
  68. Valeva, A. et al. (2001) Membrane insertion of the heptameric staphylococcal alpha-toxin pore. A domino-like structural transition that is allosterically modulated by the target cell membrane. J Biol Chem 276:14835-41 (PubMed: 11279048)
  69. Yuldasheva, L.N. et al. (2001) Lumen geometry of ion channels formed by Vibrio cholerae EL Tor cytolysin elucidated by nonelectrolyte exclusion. Biochim Biophys Acta 1512:53-63 (PubMed: 11334624)
  70. Horstick, G. et al. (2001) Plasma protein loss during surgery: beneficial effects of albumin substitution. Shock 16:9-14 (PubMed: 11442321)
  71. Lehr, H.A. et al. (2001) Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet. Circulation 104:914-20 (PubMed: 11514379)
  72. Horstick, G. et al. (2001) Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects. Circulation 104:3125-31 (PubMed: 11748112)
  73. Horstick, G. et al. (2001) C1-esterase-inhibitor treatment at early reperfusion of hemorrhagic shock reduces mesentry leukocyte adhesion and rolling. Microcirculation 8:427-33 (PubMed: 11781815)
  74. Klouche, M. et al. (2000) Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation, and proliferation. Circulation 101:1799-805 (PubMed: 10769280)
  75. Valeva, A. et al. (2000) Staphylococcal alpha-toxin: repair of a calcium-impermeable pore in the target cell membrane. Mol Microbiol 36:467-76 (PubMed: 10792732)
  76. Walev, I. et al. (2000) Potassium regulates IL-1 beta processing via calcium-independent phospholipase A2. J Immunol 164:5120-4 (PubMed: 10799869)
  77. Bhakdi, S. (2000) Pathogenesis of atherosclerosis: infectious versus immune pathogenesis. A new concept. Herz 25:84-6 (PubMed: 10829244)
  78. Han, S. et al. (2000) Identification of a unique Helicobacter species by 16S rRNA gene analysis in an abdominal abscess from a patient with X-linked hypogammaglobulinemia. J Clin Microbiol 38:2740-2 (PubMed: 10878075)
  79. Krasilnikov, O.V. et al. (2000) Electrophysiological evidence for heptameric stoichiometry of ion channels formed by Staphylococcus aureus alpha-toxin in planar lipid bilayers. Mol Microbiol 37:1372-8 (PubMed: 10998169)
  80. Han, S.R. et al. (2000) Helicobacter pylori: clonal population structure and restricted transmission within families revealed by molecular typing. J Clin Microbiol 38:3646-51 (PubMed: 11015377)
  81. Feddersen, A. et al. (2000) GyrA sequence-based typing of Legionella. Med Microbiol Immunol 189:7-11 (PubMed: 11034552)
  82. Horstick, G. et al. (2000) Plastic foil technique attenuates inflammation in mesenteric intravital microscopy. J Surg Res 94:28-34 (PubMed: 11038299)
  83. Zitzer, A. et al. (2000) Vibrio cholerae cytolysin: assembly and membrane insertion of the oligomeric pore are tightly linked and are not detectably restricted by membrane fluidity. Biochim Biophys Acta 1509:264-74 (PubMed: 11118538)
  84. Walev, I. et al. (2000) Streptolysin O-permeabilized granulocytes shed L-selectin concomitantly with ceramide generation via neutral sphingomyelinase. J Leukoc Biol 68:865-72 (PubMed: 11129654)
  85. Zitzer, A. et al. (1999) Oligomerization of Vibrio cholerae cytolysin yields a pentameric pore and has a dual specificity for cholesterol and sphingolipids in the target membrane. J Biol Chem 274:1375-80 (PubMed: 9880509)
  86. Horstick, G. et al. (1999) Surgical procedure affects physiological parameters in rat myocardial ischemia: need for mechanical ventilation. Am J Physiol 276:H472-9 (PubMed: 9950847)
  87. Biermann, C. et al. (1999) Isolation of Abiotrophia adiacens from a brain abscess which developed in a patient after neurosurgery. J Clin Microbiol 37:769-71 (PubMed: 9986849)
  88. Klouche, M. et al. (1999) Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell monolayers. Arterioscler Thromb Vasc Biol 19:784-93 (PubMed: 10073987)
  89. Han, S.R. et al. (1999) Stable and unstable amoxicillin resistance in Helicobacter pylori: should antibiotic resistance testing be performed prior to eradication therapy?. J Clin Microbiol 37:2740-1 (PubMed: 10405437)
  90. Klouche, M. et al. (1999) Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor. J Immunol 163:4583-9 (PubMed: 10510402)
  91. Bhakdi, S. et al. (1999) Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation. Arterioscler Thromb Vasc Biol 19:2348-54 (PubMed: 10521363)
  92. Abdel Ghani, E.M. et al. (1999) Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation. Biochemistry 38:15204-11 (PubMed: 10563803)
  93. Wieland, E. et al. (1999) Complement activation by oxidatively modified low-density lipoproteins. Eur J Clin Invest 29:835-41 (PubMed: 10583425)
  94. Han, S.R. et al. (1999) One-step polymerase chain reaction-based typing of Helicobacter pylori vacA gene: association with gastric histopathology. Med Microbiol Immunol 188:131-8 (PubMed: 10776843)
  95. Engel, F. et al. (1998) Bacterial cytolysin perturbs round window membrane permeability barrier in vivo: possible cause of sensorineural hearing loss in acute otitis media. Infect Immun 66:343-6 (PubMed: 9423877)
  96. Palmer, M. et al. (1998) Streptolysin O: a proposed model of allosteric interaction between a pore-forming protein and its target lipid bilayer. Biochemistry 37:2378-83 (PubMed: 9485385)
  97. Palmer, M. et al. (1998) Assembly mechanism of the oligomeric streptolysin O pore: the early membrane lesion is lined by a free edge of the lipid membrane and is extended gradually during oligomerization. EMBO J 17:1598-605 (PubMed: 9501081)
  98. Torzewski, M. et al. (1998) Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion. Arterioscler Thromb Vasc Biol 18:369-78 (PubMed: 9514405)
  99. Han, S.R. et al. (1998) vacA genotypes and genetic diversity in clinical isolates of Helicobacter pylori. Clin Diagn Lab Immunol 5:139-45 (PubMed: 9521135)
  100. Bhakdi, S. (1998) [An alternative hypothesis of the pathogenesis of atherosclerosis]. Herz 23:163-7 (PubMed: 9646097)
  101. Harris, J. et al. (1998) Cholesterol-Streptolysin O Interaction: An EM Study of Wild-Type and Mutant Streptolysin O. J Struct Biol 121:343-55 (PubMed: 9705878)
  102. Klouche, M. et al. (1998) Atherogenic properties of enzymatically degraded LDL: selective induction of MCP-1 and cytotoxic effects on human macrophages. Arterioscler Thromb Vasc Biol 18:1376-85 (PubMed: 9743225)
  103. Bhakdi, S. et al. (1998) Pore-forming bacterial cytolysins. Symp Ser Soc Appl Microbiol 27:15S-25S (PubMed: 9750358)
  104. Jahn, B. et al. (1998) Accumulation of amphotericin B in human macrophages enhances activity against Aspergillus fumigatus conidia: quantification of conidial kill at the single-cell level. Antimicrob Agents Chemother 42:2569-75 (PubMed: 9756757)
  105. Schmiedt, W. et al. (1998) Complement C6 deficiency protects against diet-induced atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol 18:1790-5 (PubMed: 9812919)
  106. Bhakdi, S. (1998) [Microbial toxins]. Wien Klin Wochenschr 110:660-8 (PubMed: 9823619)
  107. Avirutnan, P. et al. (1998) Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis. J Immunol 161:6338-46 (PubMed: 9834124)
  108. Bhakdi, S. (1998) Complement and atherogenesis: the unknown connection. Ann Med 30:503-7 (PubMed: 9920350)
  109. Horstick, G. et al. (1997) Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion. Circulation 95:701-8 (PubMed: 9024160)
  110. Malasit, P. et al. (1997) Presence of immunoglobulins, C3 and cytolytic C5b-9 complement components on the surface of erythrocytes from patients with beta-thalassaemia/HbE disease. Br J Haematol 96:507-13 (PubMed: 9054657)
  111. Ansorge, I. et al. (1997) Permeabilization of the erythrocyte membrane with streptolysin O allows access to the vacuolar membrane of Plasmodium falciparum and a molecular analysis of membrane topology. Mol Biochem Parasitol 84:259-61 (PubMed: 9084046)
  112. Kolbe, K. et al. (1997) Infectious complications during neutropenia subsequent to peripheral blood stem cell transplantation. Bone Marrow Transplant 19:143-7 (PubMed: 9116611)
  113. Zitzer, A. et al. (1997) Potent membrane-permeabilizing and cytocidal action of Vibrio cholerae cytolysin on human intestinal cells. Infect Immun 65:1293-8 (PubMed: 9119464)
  114. Valeva, A. et al. (1997) Staphylococcal alpha-toxin: the role of the N-terminus in formation of the heptameric pore — a fluorescence study. Biochim Biophys Acta 1325:281-6 (PubMed: 9168153)
  115. Zitzer, A. et al. (1997) Mode of primary binding to target membranes and pore formation induced by Vibrio cholerae cytolysin (hemolysin). Eur J Biochem 247:209-16 (PubMed: 9249028)
  116. Grimminger, F. et al. (1997) Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin. J Immunol 159:1909-16 (PubMed: 9257856)
  117. Husmann, M. et al. (1997) Simultaneous identification of campylobacters and prediction of quinolone resistance by comparative sequence analysis. J Clin Microbiol 35:2398-400 (PubMed: 9276423)
  118. Ito, W.D. et al. (1997) Infarct size measurement by triphenyltetrazolium chloride staining versus in vivo injection of propidium iodide. J Mol Cell Cardiol 29:2169-75 (PubMed: 9281448)
  119. Valeva, A. et al. (1997) Transmembrane beta-barrel of staphylococcal alpha-toxin forms in sensitive but not in resistant cells. Proc Natl Acad Sci U S A 94:11607-11 (PubMed: 9326657)
  120. Valeva, A. et al. (1997) Staphylococcal alpha-toxin: formation of the heptameric pore is partially cooperative and proceeds through multiple intermediate stages. Biochemistry 36:13298-304 (PubMed: 9341221)
  121. Palmer, M. et al. (1997) Cysteine-specific radioiodination of proteins with fluorescein maleimide. Anal Biochem 253:175-9 (PubMed: 9367500)
  122. Jahn, B. et al. (1997) Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence. Infect Immun 65:5110-7 (PubMed: 9393803)
  123. Bhakdi, S. et al. (1996) Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins. Arch Microbiol 165:73-9 (PubMed: 8593102)
  124. Valeva, A. et al. (1996) Molecular architecture of a toxin pore: a 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin. EMBO J 15:1857-64 (PubMed: 8617232)
  125. Weller, U. et al. (1996) Expression of active streptolysin O in Escherichia coli as a maltose-binding-protein–streptolysin-O fusion protein. The N-terminal 70 amino acids are not required for hemolytic activity. Eur J Biochem 236:34-9 (PubMed: 8617283)
  126. Ansorge, I. et al. (1996) Protein sorting in Plasmodium falciparum-infected red blood cells permeabilized with the pore-forming protein streptolysin O. Biochem J 315 ( Pt 1):307-14 (PubMed: 8670123)
  127. Walev, I. and Bhakdi, S. (1996) Possible reason for preferential damage to renal tubular epithelial cells evoked by amphotericin B. Antimicrob Agents Chemother 40:1116-20 (PubMed: 8723450)
  128. Saweljew, P. et al. (1996) Case of fatal systemic infection with an Aureobacterium sp.: identification of isolate by 16S rRNA gene analysis. J Clin Microbiol 34:1540-1 (PubMed: 8735113)
  129. Vollmer, P. et al. (1996) Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor. Infect Immun 64:3646-51 (PubMed: 8751912)
  130. Walev, I. et al. (1996) Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide. Proc Natl Acad Sci U S A 93:7882-7 (PubMed: 8755571)
  131. Walev, I. et al. (1996) Selective killing of human monocytes and cytokine release provoked by sphingomyelinase (beta-toxin) of Staphylococcus aureus. Infect Immun 64:2974-9 (PubMed: 8757823)
  132. Bhakdi, S. et al. (1996) Pathogenesis of sepsis syndrome: possible relevance of pore-forming bacterial toxins. Curr Top Microbiol Immunol 216:101-18 (PubMed: 8791737)
  133. Ito, W. et al. (1996) Influence of the terminal complement-complex on reperfusion injury, no-reflow and arrhythmias: a comparison between C6-competent and C6-deficient rabbits. Cardiovasc Res 32:294-305 (PubMed: 8796116)
  134. Jahn, B. et al. (1996) Colorimetric susceptibility testing for Aspergillus fumigatus: comparison of menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and Alamar blue tests. J Clin Microbiol 34:2039-41 (PubMed: 8818910)
  135. Feddersen, A. et al. (1996) Infection of the upper extremity by Mycobacterium marinum in a 3-year-old boy–diagnosis by 16S-rDNA analysis. Infection 24:47-8 (PubMed: 8852464)
  136. Palmer, M. et al. (1996) Membrane-penetrating domain of streptolysin O identified by cysteine scanning mutagenesis. J Biol Chem 271:26664-7 (PubMed: 8900142)
  137. Bhakdi, S. et al. (1995) On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety. J Exp Med 182:1959-71 (PubMed: 7500042)
  138. Jonas, D. et al. (1995) Enzyme-linked immunoassay for detection of PCR-amplified DNA of legionellae in bronchoalveolar fluid. J Clin Microbiol 33:1247-52 (PubMed: 7542266)
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